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Contribution of fetal MRI to the diagnosis of inner ear abnormalities: report of two cases.

Tilea B, Garel C, Menez F, Vuillard E, Elmaleh-Bergès M, Delezoide AL, Sebag G

Department of Paediatric Imaging, Hôpital Robert Debré, 48 Boulevard Sérurier, 75019 Paris, France.

We report two cases of fetal inner ear abnormalities diagnosed by MRI. Cerebral MRI was performed on two fetuses, at 32 and 30 weeks gestation, following US that demonstrated multiple malformations suggestive of CHARGE syndrome in one fetus and ventriculomegaly and poor visibility of the posterior fossa in the other. MRI revealed vestibular hypoplasia and agenesis of the semicircular canals in one fetus and cystic cochleas, partial vermian agenesis and an occipital meningocele in the second fetus. Both pregnancies were terminated and there was good correlation between fetal MRI, ex utero CT and fetopathological findings. The inner ears should be carefully examined when performing fetal cerebral MRI because abnormalities of the inner ear may be associated with cerebral anomalies.

Published 11 January 2006 in Pediatr Radiol, 36(2): 149-54.
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