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Water-selective spectral-spatial contrast-enhanced breast MRI for cancer detection in patients with extracapsular and injected free silicone.

Po J, Margolis DJ, Cunningham CH, Herfkens RJ, Ikeda DM, Daniel BL

New York University, Department of Radiology, 560 First Avenue, New York, NY 10016, USA.

OBJECTIVE: This study investigates the use of contrast-enhanced, T(1)-weighted, water-selective spectral-spatial 3D gradient echo magnetic resonance imaging (MRI) with magnetization transfer (3DSSMT) for detecting breast cancer in patients with intraparenchymal silicone. CONCLUSION: Water-selective 3DSSMT provides superior fat and silicone suppression in patients with free silicone as compared with conventional fat saturation. It enables direct, high-quality, high-spatial-resolution, T(1)-weighted breast MRI of contrast enhancement without the need for subtraction processing and aids diagnosis of cancer in the breast with free silicone.

Published 5 December 2006 in Magn Reson Imaging, 24(10): 1363-7.
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