MRI Research Today is a free monthly online journal that collates and summarizes the latest research about MRI, including details on magnetic resonance imaging, neuroimaging, brain tumors.

Study on the compounds containing 19F and 10B atoms in a single molecule for the application to MRI and BNCT.

Hattori Y, Asano T, Niki Y, Kondoh H, Kirihata M, Yamaguchi Y, Wakamiya T

Faculty of Science and Technology, Kinki University, Higashi-osaka, Osaka 577-8502, Japan.

Magnetic resonance imaging (MRI) and boron-neutron capture therapy (BNCT) are quite attractive techniques for diagnosis and treatment of cancer, respectively. In order to progress the study on both MRI and BNCT, the novel compounds containing 19F and 10B atoms in a single molecule were designed and synthesized. In the present paper, the syntheses and the internalization rates into tumor cells of these compounds are elucidated.

Published 4 April 2006 in Bioorg Med Chem, 14(10): 3258-62.
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