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Abdominal MRI advances in the detection of liver tumours and characterisation.

Low RN

Sharp and Children MRI Center, 7901 Frost Street, and San Diego Imaging Medical Group, 7910 Frost Street, San Diego, CA 92123, USA. rlow@ucsd.edu

With recent technical advances in hardware, software, and intravenous contrast agents, MRI has evolved into a clinically useful procedure to detect and characterise liver tumours. The combination of MRI systems with larger gradients, improved surface coils, and parallel imaging techniques have produced substantial improvements in MRI quality and speed of image acquisition. Images that previously needed several minutes to acquire can now be obtained in several seconds. The notably faster imaging capabilities of new MRI scanners are ideally suited for dynamic contrast-enhanced liver imaging in which early arterial-phase imaging is best for detecting hepatocellular carcinomas and hypervascular liver metastases. The inherent excellent soft-tissue contrast of MRI can be further improved by non-specific extracellular contrast agents and by liver-specific contrast agents. These contrast agents are now routinely used for liver imaging and improve the sensitivity and specificity of hepatobiliary MRI.

Published 1 June 2007 in Lancet Oncol, 8(6): 525-35.
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